NMRAL1 anticorps

N° du produit ABIN7116912

Cet anticorps anti-NMRAL1 est un anticorps Lapin Polyclonal détectant NMRAL1 dans ELISA, WB et IHC. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour NMRAL1 anticorps (ABIN7116912)

Antigène: NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NMRAL1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-NMRAL1 anticorps

Fonction: NMRAL1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: NmrA-like family domain containing 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur NMRAL1

Antigène: NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))

Autre désignation: NMRAL1

Sujet:

Synonyms: NmrA-like family domain-containing protein 1|NMRAL1|HSCARG

Background: Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase(ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer.

Poids moléculaire: 33 kDa

ID gène: 57407

UniProt: Q9HBL8