OCRL anticorps
Aperçu rapide pour OCRL anticorps (ABIN7117103)
Antigène
Voir toutes OCRL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- OCRL antibody
-
Purification
- Immunogen affinity purified
-
Pureté
- ≥95 % as determined by SDS-PAGE
-
Immunogène
- oculocerebrorenal syndrome of Lowe
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB: 1:500-1:2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- -20°C for 12 months
-
Date de péremption
- 12 months
-
-
- OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))
-
Autre désignation
- OCRL
-
Sujet
-
Synonyms: Inositol polyphosphate 5-phosphatase OCRL|Inositol polyphosphate 5-phosphatase OCRL-1 (OCRL-1)|Lowe oculocerebrorenal syndrome protein|Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase|OCRL|OCRL1
Background: Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate(PubMed:25869668, PubMed:7761412, PubMed:9430698). May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly(PubMed:22228094, PubMed:22543976).
-
Poids moléculaire
- 105 kDa
-
ID gène
- 4952
-
UniProt
- Q01968
-
Pathways
- Inositol Metabolic Process
Antigène
-