PDZK1 anticorps

N° du produit ABIN7117270

Cet anticorps Lapin Polyclonal détecte spécifiquement PDZK1 dans WB, ELISA et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour PDZK1 anticorps (ABIN7117270)

Antigène: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDZK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PDZK1 anticorps

Fonction: PDZK1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: PDZ domain containing 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:20 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PDZK1

Antigène: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Autre désignation: PDZK1

Sujet:

Synonyms: Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3)|CFTR-associated protein of 70 kDa|Na(+)/H(+) exchanger regulatory factor 3|Na/Pi cotransporter C-terminal-associated protein 1 (NaPi-Cap1)|PDZ domain-containing protein 1|Sodium-hydrogen exchanger regulatory factor 3|PDZK1|CAP70|NHERF3|PDZD1

Background: This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Poids moléculaire: 67 kDa

ID gène: 5174

UniProt: Q5T2W1