Pellino 1 anticorps
Aperçu rapide pour Pellino 1 anticorps (ABIN7117275)
Antigène
Voir toutes Pellino 1 (PELI1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- PELI1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- pellino homolog 1(Drosophila)
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IP: 1:200-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))
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Autre désignation
- PELI1
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Sujet
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Synonyms: E3 ubiquitin-protein ligase pellino homolog 1 (Pellino-1)|Pellino-related intracellular-signaling molecule|RING-type E3 ubiquitin transferase pellino homolog 1|PELI1|PRISM
Background: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation.
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Poids moléculaire
- 46 kDa
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ID gène
- 57162
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UniProt
- Q96FA3
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Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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