PCM1 anticorps
Aperçu rapide pour PCM1 anticorps (ABIN7117316)
Antigène
Voir toutes PCM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- PCM1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- pericentriolar material 1
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Isotype
- IgG
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Indications d'application
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- PCM1 (Pericentriolar Material 1 (PCM1))
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Autre désignation
- PCM1
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Sujet
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Synonyms: Pericentriolar material 1 protein (PCM-1, hPCM-1)|PCM1
Background: The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.
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Poids moléculaire
- 300 kDa
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ID gène
- 5108
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UniProt
- Q15154
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Pathways
- Stem Cell Maintenance, M Phase, Maintenance of Protein Location
Antigène
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