PHF2 anticorps
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- Antigène Voir toutes PHF2 Anticorps
- PHF2 (PHD Finger Protein 2 (PHF2))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PHF2 est non-conjugé
- Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- PHD finger protein 2
- Isotype
- IgG
- Top Product
- Discover our top product PHF2 Anticorps primaire
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- Indications d'application
- WB: 1:200-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
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- Antigène
- PHF2 (PHD Finger Protein 2 (PHF2))
- Autre désignation
- PHF2 (PHF2 Produits)
- Synonymes
- anticorps CENP-35, anticorps GRC5, anticorps JHDM1E, anticorps im:4200679, anticorps phf8, anticorps wu:fa14c10, anticorps PHD finger protein 2, anticorps PHF2, anticorps Phf2, anticorps phf2
- Sujet
- Synonyms:GRC5, JHDM1E, KIAA0662, PHD finger protein 2, PHF2 Background:Lysine demethylase that demethylates both histones and non-histone proteins. Enzymatically inactive by itself, and becomes active following phosphorylation by PKA: forms a complex with ARID5B and mediates demethylation of methylated ARID5B. Demethylation of ARID5B leads to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3(H3K9me2), followed by transcription activation of target genes. The PHF2-ARID5B complex acts as a coactivator of HNF4A in liver. PHF2 is recruited to trimethylated 'Lys-4' of histone H3(H3K4me3) at rDNA promoters and promotes expression of rDNA.
- Poids moléculaire
- 100 kDa, 150 kDa
- ID gène
- 5253
- UniProt
- O75151
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