PHACTR4 anticorps

N° du produit ABIN7117389

Cet anticorps anti-PHACTR4 est un anticorps Lapin Polyclonal détectant PHACTR4 dans WB, ELISA et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour PHACTR4 anticorps (ABIN7117389)

Antigène: PHACTR4 (Phosphatase and Actin Regulator 4 (PHACTR4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHACTR4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-PHACTR4 anticorps

Fonction: PHACTR4 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: phosphatase and actin regulator 4

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PHACTR4

Antigène: PHACTR4 (Phosphatase and Actin Regulator 4 (PHACTR4))

Autre désignation: PHACTR4

Sujet:

Synonyms: Phosphatase and actin regulator 4|PHACTR4

Background: Regulator of protein phosphatase 1(PP1) required for neural tube and optic fissure closure, and enteric neural crest cell(ENCCs) migration during development. Acts as an activator of PP1 by interacting with PPP1CA and preventing phosphorylation of PPP1CA at 'Thr-320'. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells(ENCCs) by activating PP1, leading to dephosphorylation and subsequent activation of cofilin(COF1 or COF2) and repression of the integrin signaling through the RHO/ROCK pathway(By similarity).

Poids moléculaire: 71-85 kDa

ID gène: 65979

UniProt: Q8IZ21

Pathways: Tube Formation