PLCD4 anticorps

N° du produit ABIN7117488

Cet anticorps anti-PLCD4 est un anticorps Lapin Polyclonal détectant PLCD4 dans IHC et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour PLCD4 anticorps (ABIN7117488)

Antigène: PLCD4 (Phospholipase C, delta 4 (PLCD4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLCD4 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-PLCD4 anticorps

Fonction: PLCD4 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: phospholipase C, delta 4

Isotype: IgG

Information d'application

Indications d'application: IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PLCD4

Antigène: PLCD4 (Phospholipase C, delta 4 (PLCD4))

Autre désignation: PLCD4

Sujet:

Synonyms: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (hPLCD4)|Phosphoinositide phospholipase C-delta-4|Phospholipase C-delta-4 (PLC-delta-4)|PLCD4

Background: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate(PIP2) to generate 2 second messenger molecules diacylglycerol(DAG) and inositol 1,4,5-trisphosphate(IP3). DAG mediates the activation of protein kinase C(PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.

ID gène: 84812

UniProt: Q9BRC7

Pathways: Inositol Metabolic Process