PLAU anticorps

N° du produit ABIN7117556

L’anticorps Lapin Polyclonal anti-PLAU a été validé pour WB, ELISA, IHC, IP et IF. Il convient pour détecter PLAU dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PLAU anticorps (ABIN7117556)

Antigène: PLAU (Plasminogen Activator, Urokinase (PLAU))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAU est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Détail du produit anti-PLAU anticorps

Fonction: PLAU antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: plasminogen activator, urokinase

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:1000, IHC:1:20-1:200,IF: 1:20-1:200, IP: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PLAU

Antigène: PLAU (Plasminogen Activator, Urokinase (PLAU))

Autre désignation: PLAU

Sujet:

Synonyms: Urokinase-type plasminogen activator (U-plasminogen activator, uPA)|Urokinase-type plasminogen activator long chain A|Urokinase-type plasminogen activator short chain A|Urokinase-type plasminogen activator chain B|PLAU

Background: PLAU(Urokinase-type plasminogen activator) is also named as uPA and belongs to the peptidase S1 family.UPA initiates a proteolytic cascade, which degrades extracellular matrix during tissue growth and remodelling.The secreted proform of UPA is activated after binding to a specific high affinity cell surface receptor. Secreted UPA is exposed to rapid inactivation in the pericellular space by plasminogen activator inhibitor-1(PAI-1), which is stored in the extracellular matrix bound to vitronectin(PMID:9665342).It has 2 isoforms produced by alternative splicing.Defects in PLAU are the cause of Quebec platelet disorder(QPD).

Poids moléculaire: 54 kDa

ID gène: 5328

UniProt: P00749

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration