PQBP1 anticorps

N° du produit ABIN7117652

L’anticorps Lapin Polyclonal anti-PQBP1 a été validé pour WB et ELISA. Il convient pour détecter PQBP1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PQBP1 anticorps (ABIN7117652)

Antigène: PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PQBP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PQBP1 anticorps

Fonction: PQBP1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: polyglutamine binding protein 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PQBP1

Antigène: PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))

Autre désignation: PQBP1

Sujet:

Synonyms: Polyglutamine-binding protein 1 (PQBP-1)|38 kDa nuclear protein containing a WW domain (Npw38)|Polyglutamine tract-binding protein 1|PQBP1|NPW38

Background: Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species(PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.

Poids moléculaire: 38 kDa, 30 kDa

ID gène: 10084

UniProt: O60828

Pathways: Ribonucleoprotein Complex Subunit Organization