POLR3K anticorps

N° du produit ABIN7117684

Cet anticorps Lapin Polyclonal détecte spécifiquement POLR3K dans WB, ELISA, IHC et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour POLR3K anticorps (ABIN7117684)

Antigène: POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLR3K est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-POLR3K anticorps

Fonction: POLR3K antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: polymerase(RNA) III(DNA directed) polypeptide K, 12.3 kDa

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur POLR3K

Antigène: POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))

Autre désignation: POLR3K

Sujet:

Synonyms: DNA-directed RNA polymerase III subunit RPC10 (RNA polymerase III subunit C10)|DNA-directed RNA polymerase III subunit K|RNA polymerase III 12.5 kDa subunit (RPC12.5)|RNA polymerase III subunit C11 (HsC11p, RPC11, hRPC11)|POLR3K|RPC11

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs(EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity).

Poids moléculaire: 12 kDa

ID gène: 51728

UniProt: Q9Y2Y1