Gastrin-Releasing Peptide anticorps (AA 1-148)
Aperçu rapide pour Gastrin-Releasing Peptide anticorps (AA 1-148) (ABIN7117775)
Antigène
Voir toutes Gastrin-Releasing Peptide (GRP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 1-148
-
Fonction
- GRP antibody
-
Purification
- Immunogen affinity purified
-
Pureté
- ≥95 % as determined by SDS-PAGE
-
Immunogène
-
Immunogen sequence: 1-148aa
Immunogen: gastrin-releasing peptide
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- -20°C for 12 months
-
Date de péremption
- 12 months
-
-
- Gastrin-Releasing Peptide (GRP)
-
Autre désignation
- GRP
-
Sujet
-
Synonyms: Gastrin-releasing peptide (GRP)|Neuromedin-C Alternative names: GRP-10|GRP18-27|GRP
Background: Gastrin-releasing peptide, also known as GRP, is normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets, and its main function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. Its 148-amino acid preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27-amino acid gastrin-releasing peptide or the 10-amino acid neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation.These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate.
-
Poids moléculaire
- 16 kDa, 32 kDa
-
ID gène
- 2922
-
UniProt
- P07492
-
Pathways
- Peptide Hormone Metabolism, Hormone Activity
Antigène
-