PDIA3 anticorps

N° du produit ABIN7117935

Cet anticorps anti-PDIA3 est un anticorps Lapin Polyclonal détectant PDIA3 dans WB, IHC, ELISA, IF, IP et FACS. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour PDIA3 anticorps (ABIN7117935)

Antigène: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDIA3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Détail du produit anti-PDIA3 anticorps

Fonction: PDIA3 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: protein disulfide isomerase family A, member 3

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2400, IP: 1:1000-1:4000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PDIA3

Antigène: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Autre désignation: PDIA3

Sujet:

Synonyms: Protein disulfide-isomerase A3|58 kDa glucose-regulated protein|58 kDa microsomal protein (p58)|Disulfide isomerase ER-60|Endoplasmic reticulum resident protein 57 (ER protein 57, ERp57)|Endoplasmic reticulum resident protein 60 (ER protein 60, ERp60)|PDIA3|ERP57|ERP60|GRP58

Background: PDIA3, also named as P58, ER60, ERp57, ERp60, ERp61, GRP57, GRP58 and PI-PLC, is a member of the PDI family, participates in the oxidation, reduction, and isomerization of disulfide bonds for correct folding of secretory proteins before modification and transport in the endoplasmic reticulum. It is associated with apoptosis or inhibition of cancer cell growth. PDIA3 was once thought to be a phospholipase, however, it has been demonstrated that this protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and PDIA3 mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

Poids moléculaire: 57 kDa

UniProt: P30101

Pathways: Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis