PKMYT1 anticorps

N° du produit ABIN7117978

Cet anticorps Lapin Polyclonal détecte spécifiquement PKMYT1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PKMYT1 anticorps (ABIN7117978)

Antigène: PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKMYT1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PKMYT1 anticorps

Fonction: PKMYT1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: protein kinase, membrane associated tyrosine/threonine 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PKMYT1

Antigène: PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))

Autre désignation: PKMYT1

Sujet:

Synonyms: Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase|Myt1 kinase|PKMYT1|MYT1

Background: Acts as a negative regulator of entry into mitosis(G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.

Poids moléculaire: 55 kDa

ID gène: 9088

UniProt: Q99640

Pathways: Mitotic G1-G1/S Phases, M Phase