PPM1B anticorps
Aperçu rapide pour PPM1B anticorps (ABIN7118038)
Antigène
Voir toutes PPM1B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- PPM1B antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- protein phosphatase 1B(formerly 2C), magnesium-dependent, beta isoform
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))
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Autre désignation
- PPM1B
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Sujet
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Synonyms: Protein phosphatase 1B|Protein phosphatase 2C isoform beta (PP2C-beta)|PPM1B|PP2CB
Background: Enzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
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Poids moléculaire
- 50-53 kDa
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ID gène
- 5495
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UniProt
- O75688
Antigène
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