PTPMT1 anticorps
Aperçu rapide pour PTPMT1 anticorps (ABIN7118052)
Antigène
Voir toutes PTPMT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- PTPMT1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- protein tyrosine phosphatase, mitochondrial 1
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Isotype
- IgG
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Indications d'application
- WB: 1:200-1:1000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))
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Autre désignation
- PTPMT1
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Sujet
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Synonyms: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1|PTEN-like phosphatase|Phosphoinositide lipid phosphatase|Protein-tyrosine phosphatase mitochondrial 1|PTPMT1|MOSP|PLIP
Background: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate(PGP) to phosphatidylglycerol(PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells(By similarity).
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Poids moléculaire
- 21-23 kDa
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ID gène
- 114971
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UniProt
- Q8WUK0
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Pathways
- Inositol Metabolic Process
Antigène
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