RAB23 anticorps

N° du produit ABIN7118198

L’anticorps Lapin Polyclonal anti-RAB23 a été validé pour WB, ELISA, IHC et IP. Il convient pour détecter RAB23 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RAB23 anticorps (ABIN7118198)

Antigène: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB23 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-RAB23 anticorps

Fonction: RAB23 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: RAB23, member RAS oncogene family

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RAB23

Antigène: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Autre désignation: RAB23

Sujet:

Synonyms: Ras-related protein Rab-23|RAB23

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes.

Poids moléculaire: 27 kDa

ID gène: 51715

UniProt: Q9ULC3

Pathways: Tube Formation