RQCD1 anticorps
Aperçu rapide pour RQCD1 anticorps (ABIN7118331)
Antigène
Voir toutes RQCD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- CNOT9 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- RCD1 required for cell differentiation1 homolog(S. pombe)
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- RQCD1 (RCD1 Required For Cell Differentiation1 Homolog (RQCD1))
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Autre désignation
- CNOT9
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Sujet
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Synonyms: CCR4-NOT transcription complex subunit 9|Cell differentiation protein RQCD1 homolog (Rcd-1)|CNOT9|RCD1|RQCD1
Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB-and JUN-dependent transcription. May play a role in cell differentiation(By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T(in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.
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Poids moléculaire
- 30-40 kDa
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ID gène
- 9125
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UniProt
- Q92600
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Antigène
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