RECQL5 anticorps
Aperçu rapide pour RECQL5 anticorps (ABIN7118358)
Antigène
Voir toutes RECQL5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- RECQL5 antibody
-
Purification
- Immunogen affinity purified
-
Pureté
- ≥95 % as determined by SDS-PAGE
-
Immunogène
- RecQ protein-like 5
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- -20°C for 12 months
-
Date de péremption
- 12 months
-
-
- RECQL5 (RecQ Protein-Like 5 (RECQL5))
-
Autre désignation
- RECQL5
-
Sujet
-
Synonyms: ATP-dependent DNA helicase Q5|DNA helicase, RecQ-like type 5 (RecQ5)|RecQ protein-like 5|RECQL5|RECQ5
Background: Isoform beta is a DNA helicase that plays an important role in DNA replication, transcription and repair. Inhibits elongation of stalled transcripts at DNA damage sites by binding to the RNA polymerase II subunit POLR2A and blocking the TCEA1 binding site. Required for mitotic chromosome separation after cross-over events and cell cycle progress. Required for efficient DNA repair, including repair of inter-strand cross-links. Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination.
-
Poids moléculaire
- 50-60 kDa
-
ID gène
- 9400
-
UniProt
- O94762
Antigène
-