RTEL1 anticorps

N° du produit ABIN7118387

L’anticorps Lapin Polyclonal anti-RTEL1 a été validé pour ELISA et WB. Il convient pour détecter RTEL1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RTEL1 anticorps (ABIN7118387)

Antigène: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RTEL1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-RTEL1 anticorps

Fonction: RTEL1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: regulator of telomere elongation helicase 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RTEL1

Antigène: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Autre désignation: RTEL1

Sujet:

Synonyms: Regulator of telomere elongation helicase 1|Novel helicase-like|RTEL1|C20orf41|KIAA1088|NHL

Background: ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing(SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.

Poids moléculaire: 133 kDa

ID gène: 51750

UniProt: Q9NZ71