RTEL1 anticorps

N° du produit ABIN7118387

Détail du produit anti-RTEL1 anticorps

Antigène: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RTEL1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: regulator of telomere elongation helicase 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur RTEL1

Antigène: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Autre désignation: RTEL1 (RTEL1 Produits)

Synonymes: anticorps F18B13.3, anticorps F18B13_3, anticorps C20orf41, anticorps DKCB5, anticorps NHL, anticorps RTEL, anticorps bK3184A7.3, anticorps AI451565, anticorps AW540478, anticorps Rtel, anticorps RGD1306721, anticorps zgc:113114, anticorps regulator of telomere elongation helicase 1, anticorps RAD3-like DNA-binding helicase protein, anticorps RTEL1, anticorps rtel1, anticorps AT1G79950, anticorps LOC100286037, anticorps Rtel1

Sujet: Synonyms:C20orf41, KIAA1088, NHL Background:ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing(SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.

Poids moléculaire: 133 kDa

ID gène: 51750

UniProt: Q9NZ71