RFX3 anticorps

N° du produit ABIN7118388

Cet anticorps anti-RFX3 est un anticorps Lapin Polyclonal détectant RFX3 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour RFX3 anticorps (ABIN7118388)

Antigène: RFX3 (Regulatory Factor X 3 (RFX3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFX3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RFX3 anticorps

Fonction: RFX3 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: regulatory factor X, 3(influences HLA class II expression)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RFX3

Antigène: RFX3 (Regulatory Factor X 3 (RFX3))

Autre désignation: RFX3

Sujet:

Synonyms: Transcription factor RFX3|Regulatory factor X 3|RFX3

Background: Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development. Essential for the differentiation of nodal monocilia and left-right asymmetry specification during embryogenesis. Required for the biogenesis of motile cilia by governing growth and beating efficiency of motile cells. Also required for ciliated ependymal cell differentiation. Regulates the expression of genes involved in ciliary assembly(DYNC2LI1, FOXJ1 and BBS4) and genes involved in ciliary motility(DNAH11, DNAH9 and DNAH5)(By similarity). Together with RFX6, participates in the differentiation of 4 of the 5 islet cell types during endocrine pancreas development, with the exception of pancreatic PP(polypeptide-producing) cells. Regulates transcription by forming a heterodimer with another RFX protein and binding to the X-box in the promoter of target genes(PubMed:20148032). Represses transcription of MAP1A in non-neuronal cells but not in neuronal cells(PubMed:12411430).

Poids moléculaire: 70-79 kDa

ID gène: 5991

UniProt: P48380