Riboflavin Kinase anticorps
Aperçu rapide pour Riboflavin Kinase anticorps (ABIN7118514)
Antigène
Voir toutes Riboflavin Kinase (RFK) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- RFK antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- riboflavin kinase
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- Riboflavin Kinase (RFK)
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Autre désignation
- RFK
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Sujet
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Synonyms: Riboflavin kinase|ATP:riboflavin 5'-phosphotransferase|Flavokinase|RFK
Background: Catalyzes the phosphorylation of riboflavin(vitamin B2) to form flavin-mononucleotide(FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species(ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase.
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Poids moléculaire
- 18 kDa
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ID gène
- 55312
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UniProt
- Q969G6
Antigène
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