RNF212 anticorps

N° du produit ABIN7118647

Cet anticorps Lapin Polyclonal détecte spécifiquement RNF212 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour RNF212 anticorps (ABIN7118647)

Antigène: RNF212 (Ring Finger Protein 212 (RNF212))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF212 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RNF212 anticorps

Fonction: RNF212 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ring finger protein 212

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RNF212

Antigène: RNF212 (Ring Finger Protein 212 (RNF212))

Autre désignation: RNF212

Sujet:

Synonyms: Probable E3 SUMO-protein ligase RNF212|Probable E3 SUMO-protein transferase RNF212|RING finger protein 212|RNF212

Background: SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins(MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination(By similarity).

Poids moléculaire: 22 kDa

ID gène: 285498

UniProt: Q495C1