RNF6 anticorps

N° du produit ABIN7118660

L’anticorps anti-RNF6 Polyclonal Lapin est utilisé pour la détection de RNF6 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour RNF6 anticorps (ABIN7118660)

Antigène: RNF6 (RING Finger Protein 6 (RNF6))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-RNF6 anticorps

Fonction: RNF6 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ring finger protein(C3H2C3 type) 6

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RNF6

Antigène: RNF6 (RING Finger Protein 6 (RNF6))

Autre désignation: RNF6

Sujet:

Synonyms: E3 ubiquitin-protein ligase RNF6|RNF6|SPG2

Background: E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.

Poids moléculaire: 78 kDa

ID gène: 6049

UniProt: Q9Y252

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size