RBPMS anticorps
Aperçu rapide pour RBPMS anticorps (ABIN7118698)
Antigène
Voir toutes RBPMS AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- RBPMS antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- RNA binding protein with multiple splicing
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))
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Autre désignation
- RBPMS
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Sujet
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Synonyms: RNA-binding protein with multiple splicing (RBP-MS)|Heart and RRM expressed sequence (Hermes)|RBPMS|HERMES
Background: Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins(PubMed:26347403). Binds to poly(A) RNA(PubMed:17099224, PubMed:26347403).
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Poids moléculaire
- 28-30 kDa
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ID gène
- 11030
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UniProt
- Q93062
Antigène
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