SAFB anticorps

N° du produit ABIN7118797

Cet anticorps Lapin Polyclonal détecte spécifiquement SAFB dans WB, IHC, IF et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour SAFB anticorps (ABIN7118797)

Antigène: SAFB (Scaffold Attachment Factor B (SAFB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAFB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Détail du produit anti-SAFB anticorps

Fonction: SAFB antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: scaffold attachment factor B

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SAFB

Antigène: SAFB (Scaffold Attachment Factor B (SAFB))

Autre désignation: SAFB

Sujet:

Synonyms: Scaffold attachment factor B1 (SAF-B, SAF-B1)|HSP27 estrogen response element-TATA box-binding protein (HSP27 ERE-TATA-binding protein)|SAFB|HAP|HET|SAFB1

Background: Binds to scaffold/matrix attachment region(S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex(consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing(By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter(By similarity). Can inhibit cell proliferation.

Poids moléculaire: 150 kDa

ID gène: 6294

UniProt: Q15424

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway