SRGAP2 anticorps (AA 780-940)

N° du produit ABIN7119134

L’anticorps Lapin Polyclonal anti-SRGAP2 a été validé pour WB, ELISA et IHC. Il convient pour détecter SRGAP2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SRGAP2 anticorps (AA 780-940) (ABIN7119134)

Antigène: SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRGAP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SRGAP2 anticorps

Épitope: AA 780-940

Fonction: SRGAP2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 780-940aa

Immunogen: SLIT-ROBO Rho GTPase activating protein 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SRGAP2

Antigène: SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))

Autre désignation: SRGAP2

Sujet:

Synonyms: SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2)|Formin-binding protein 2|Rho GTPase-activating protein 34|SRGAP2|ARHGAP34|FNBP2|KIAA0456|SRGAP2A

Background: RAC1 GTPase activating protein(GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. Plays an important role in different aspects of neuronal morphogenesis and migration mainly during development of the cerebral cortex. This includes the biogenesis of neurites, where it is required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. Also stimulates the branching of the leading process and negatively regulates neuron radial migration in the cerebral cortex. Its interaction and inhibition by SRGAP2C reduces the rate of spine maturation, alters dendritic spine morphology and density and indirectly increases neuronal migration. It may have implications for cognition, learning and memory. In non-neuronal cells, it may also play a role in cell migration by regulating the formation of lamellipodia and filopodia.

Poids moléculaire: 120-140 kDa

ID gène: 23380

UniProt: O75044