SLC39A8 anticorps
Aperçu rapide pour SLC39A8 anticorps (ABIN7119306)
Antigène
Voir toutes SLC39A8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- SLC39A8 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- solute carrier family 39(zinc transporter), member 8
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- SLC39A8 (Solute Carrier Family 39 (Zinc Transporter), Member 8 (SLC39A8))
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Autre désignation
- SLC39A8
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Sujet
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Synonyms: Metal cation symporter ZIP8|BCG-induced integral membrane protein in monocyte clone 103 protein|LIV-1 subfamily of ZIP zinc transporter 6 (LZT-Hs6)|Solute carrier family 39 member 8|Zrt- and Irt-like protein 8 (ZIP-8)|SLC39A8|BIGM103|ZIP8
Background: SLC39A8 also known as ZIP8 belongs to the ZIP family of metal ion transporters which function to transport zinc and/or other metal ion substrates from the extracellular space or organellar lumen into the cytoplasm. Recently it was found that Zip8 expression is upregulated in human monocytes in response to LPS, TNF-α, and live bacteria, facilitating cytoprotection during the early inflammation. Besides zinc ZIP8 can also transport cadmium and manganese efficiently. It is predicted that ZIP8 contains 3 potential N-linked glycosylation sites and is subject to glycosylation, which may account for the presences of multiple molecular weights, such as 43 kDa, 49 kDa, 60 kDa, 75-90 kDa, 150 kDa, and 200 kDa.
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Poids moléculaire
- 53 kDa, 75-90 kDa
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ID gène
- 64116
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UniProt
- Q9C0K1
Antigène
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