Sorbs2 anticorps
Aperçu rapide pour Sorbs2 anticorps (ABIN7119344)
Antigène
Voir toutes Sorbs2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- SORBS2 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- sorbin and SH3 domain containing 2
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Isotype
- IgG
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Indications d'application
- IP: 1:200-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))
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Autre désignation
- SORBS2
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Sujet
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Synonyms: Sorbin and SH3 domain-containing protein 2|Arg-binding protein 2 (ArgBP2)|Arg/Abl-interacting protein 2|Sorbin|SORBS2|ARGBP2|KIAA0777
Background: Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12(PubMed:18559503). Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.
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ID gène
- 8470
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UniProt
- O94875
Antigène
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