SNX9 anticorps

N° du produit ABIN7119367

Cet anticorps Lapin Polyclonal détecte spécifiquement SNX9 dans WB, ELISA, IF et IP. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour SNX9 anticorps (ABIN7119367)

Antigène: SNX9 (Sorting Nexin 9 (SNX9))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX9 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-SNX9 anticorps

Fonction: SNX9 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: sorting nexin 9

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SNX9

Antigène: SNX9 (Sorting Nexin 9 (SNX9))

Autre désignation: SNX9

Sujet:

Synonyms: Sorting nexin-9|SH3 and PX domain-containing protein 1 (Protein SDP1)|SH3 and PX domain-containing protein 3A|SNX9|SH3PX1|SH3PXD3A

Background: Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate.

Poids moléculaire: 70-78 kDa

ID gène: 51429

UniProt: Q9Y5X1