SPO11 anticorps
Aperçu rapide pour SPO11 anticorps (ABIN7119445)
Antigène
Voir toutes SPO11 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- SPO11 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- SPO11 meiotic protein covalently bound to DSB homolog
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- SPO11 (SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))
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Autre désignation
- SPO11
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Sujet
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Synonyms: Meiotic recombination protein SPO11|Cancer/testis antigen 35 (CT35)|SPO11
Background: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks(DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2.
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Poids moléculaire
- 55-70 kDa
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ID gène
- 23626
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UniProt
- Q9Y5K1
Antigène
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