SQLE anticorps

N° du produit ABIN7119452

L’anticorps Lapin Polyclonal anti-SQLE a été validé pour WB, IHC, ELISA, IF et IP. Il convient pour détecter SQLE dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SQLE anticorps (ABIN7119452)

Antigène: SQLE (Squalene Epoxidase (SQLE))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SQLE est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-SQLE anticorps

Fonction: SQLE antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: squalene epoxidase

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SQLE

Antigène: SQLE (Squalene Epoxidase (SQLE))

Autre désignation: SQLE

Sujet:

Synonyms: Squalene monooxygenase|Squalene epoxidase (SE)|SQLE|ERG1

Background: SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase(HMGR, considered as rate limiting). It is also posttranslationally regulated by cholesterol-dependent proteasomal degradation.(PMID:21356516) The MW of SQLE is about 64kd.

Poids moléculaire: 64 kDa

ID gène: 6713

UniProt: Q14534