SKAP2 anticorps

N° du produit ABIN7119461

L’anticorps Lapin Polyclonal anti-SKAP2 a été validé pour WB, ELISA, IHC et IF. Il convient pour détecter SKAP2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SKAP2 anticorps (ABIN7119461)

Antigène: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKAP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SKAP2 anticorps

Fonction: SKAP2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: src kinase associated phosphoprotein 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100, IF: 1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SKAP2

Antigène: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Autre désignation: SKAP2

Sujet:

Synonyms: Src kinase-associated phosphoprotein 2|Pyk2/RAFTK-associated protein|Retinoic acid-induced protein 70|SKAP55 homolog (SKAP-55HOM, SKAP-HOM)|Src family-associated phosphoprotein 2|Src kinase-associated phosphoprotein 55-related protein|Src-associated adapter protein with PH and SH3 domains|SKAP2|PRAP|RA70|SAPS|SCAP2|SKAP55R

Background: The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 50 kDa

ID gène: 8935

UniProt: O75563