STT3A anticorps

N° du produit ABIN7119563

L’anticorps Lapin Polyclonal anti-STT3A a été validé pour ELISA, IHC, WB et IF. Il convient pour détecter STT3A dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour STT3A anticorps (ABIN7119563)

Antigène: STT3A (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog A (STT3A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STT3A est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-STT3A anticorps

Fonction: STT3A antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: STT3, subunit of the oligosaccharyltransferase complex, homolog A

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000-1:5000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur STT3A

Antigène: STT3A (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog A (STT3A))

Autre désignation: STT3A

Sujet:

Synonyms: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A, STT3-A)|B5|Integral membrane protein 1|Transmembrane protein TMC|STT3A|ITM1|TMC

Background: Catalytic subunit of the N-oligosaccharyl transferase(OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum(ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.

Poids moléculaire: 100 kDa

ID gène: 3703

UniProt: P46977