SENP3 anticorps

N° du produit ABIN7119591

Cet anticorps anti-SENP3 est un anticorps Lapin Polyclonal détectant SENP3 dans WB, ELISA et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SENP3 anticorps (ABIN7119591)

Antigène: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SENP3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-SENP3 anticorps

Fonction: SENP3 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: SUMO1/sentrin/SMT3 specific peptidase 3

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SENP3

Antigène: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Autre désignation: SENP3

Sujet:

Synonyms: Sentrin-specific protease 3|SUMO-1-specific protease 3|Sentrin/SUMO-specific protease SENP3|SENP3|SSP3|SUSP3

Background: Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP(5FMC) complex, the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.

Poids moléculaire: 65-70 kDa

ID gène: 26168

UniProt: Q9H4L4