ST5 anticorps
Aperçu rapide pour ST5 anticorps (ABIN7119601)
Antigène
Voir toutes ST5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- DENND2B antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- suppression of tumorigenicity 5
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- ST5 (Suppression of Tumorigenicity 5 (ST5))
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Autre désignation
- DENND2B
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Sujet
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Synonyms: DENN domain-containing protein 2B|HeLa tumor suppression 1|Suppression of tumorigenicity 5 protein|DENND2B|HTS1|ST5
Background: Guanine nucleotide exchange factor(GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth.
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Poids moléculaire
- 82 kDa, 70 kDa
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ID gène
- 6764
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UniProt
- P78524
Antigène
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