SYNGAP1 anticorps

N° du produit ABIN7119648

Cet anticorps anti-SYNGAP1 est un anticorps Lapin Polyclonal détectant SYNGAP1 dans WB, ELISA et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SYNGAP1 anticorps (ABIN7119648)

Antigène: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYNGAP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-SYNGAP1 anticorps

Fonction: SYNGAP1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: synaptic Ras GTPase activating protein 1 homolog(rat)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SYNGAP1

Antigène: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Autre désignation: SYNGAP1

Sujet:

Synonyms: Ras/Rap GTPase-activating protein SynGAP|Neuronal RasGAP|Synaptic Ras GTPase-activating protein 1 (Synaptic Ras-GAP 1)|SYNGAP1|KIAA1938

Background: Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits(By similarity).

Poids moléculaire: 148 kDa

ID gène: 8831

UniProt: Q96PV0

Pathways: Regulation of long-term Neuronal Synaptic Plasticity