TBC1D17 anticorps (AA 1-350)
Aperçu rapide pour TBC1D17 anticorps (AA 1-350) (ABIN7119799)
Antigène
Voir toutes TBC1D17 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-350
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Fonction
- TBC1D17 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
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Immunogen sequence: 1-350aa
Immunogen: TBC1 domain family, member 17
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))
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Autre désignation
- TBC1D17
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Sujet
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Synonyms: TBC1 domain family member 17|TBC1D17
Background: Probable GTPase-activating protein for Rab8, its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor(TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment(ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50, the function requires its catalytic activity, however, the involved Rab is not known.
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Poids moléculaire
- 73-100 kDa
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ID gène
- 79735
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UniProt
- Q9HA65
Antigène
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