TELO2 anticorps
Aperçu rapide pour TELO2 anticorps (ABIN7119824)
Antigène
Voir toutes TELO2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- TELO2 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- TEL2, telomere maintenance 2, homolog
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))
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Autre désignation
- TELO2
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Sujet
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Synonyms: Telomere length regulation protein TEL2 homolog|Protein clk-2 homolog (hCLK2)|TELO2|KIAA0683
Background: Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
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Poids moléculaire
- 92 kDa
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ID gène
- 9894
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UniProt
- Q9Y4R8
Antigène
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