TELO2 anticorps

N° du produit ABIN7119825

Cet anticorps anti-TELO2 est un anticorps Souris Monoclonal détectant TELO2 dans WB, ELISA, IHC, IF et IP. Adapté pour Humain.

Aperçu rapide pour TELO2 anticorps (ABIN7119825)

Antigène: TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TELO2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 8B6

Détail du produit anti-TELO2 anticorps

Fonction: TELO2 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: TEL2, telomere maintenance 2, homolog

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:1000-1:4000, IP: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur TELO2

Antigène: TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))

Autre désignation: TELO2

Sujet:

Synonyms: Telomere length regulation protein TEL2 homolog|Protein clk-2 homolog (hCLK2)|TELO2|KIAA0683

Background: Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.

Poids moléculaire: 92 kDa

ID gène: 9894

UniProt: Q9Y4R8