TTI1 anticorps

N° du produit ABIN7119826

Cet anticorps Lapin Polyclonal détecte spécifiquement TTI1 dans ELISA, WB et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour TTI1 anticorps (ABIN7119826)

Antigène: TTI1 (TELO2 Interacting Protein 1 (TTI1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTI1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-TTI1 anticorps

Fonction: TTI1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: KIAA0406

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:500-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur TTI1

Antigène: TTI1 (TELO2 Interacting Protein 1 (TTI1))

Autre désignation: TTI1

Sujet:

Synonyms: TELO2-interacting protein 1 homolog|Protein SMG10|TTI1|KIAA0406|SMG10

Background: Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.

Poids moléculaire: 122 kDa

ID gène: 9675

UniProt: O43156