Tescalcin anticorps
Aperçu rapide pour Tescalcin anticorps (ABIN7119839)
Antigène
Voir toutes Tescalcin (TESC) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- TESC antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- tescalcin
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- Tescalcin (TESC)
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Autre désignation
- TESC
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Sujet
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Synonyms: Calcineurin B homologous protein 3|Tescalcin (TSC)|TESC|CHP3
Background: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.
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Poids moléculaire
- 25-30 kDa
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ID gène
- 54997
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UniProt
- Q96BS2
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Pathways
- Proton Transport
Antigène
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