THOC7 anticorps
Aperçu rapide pour THOC7 anticorps (ABIN7119929)
Antigène
Voir toutes THOC7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- THOC7 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- THO complex 7 homolog(Drosophila)
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- THOC7 (THO Complex 7 (THOC7))
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Autre désignation
- THOC7
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Sujet
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Synonyms: THO complex subunit 7 homolog|Functional spliceosome-associated protein 24 (fSAP24)|Ngg1-interacting factor 3-like protein 1-binding protein 1 (NIF3L1-binding protein 1)|hTREX30|THOC7|NIF3L1BP1
Background: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex(EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus(KSHV) intronless mRNAs and infectious virus production.
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Poids moléculaire
- 24 kDa
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ID gène
- 80145
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UniProt
- Q6I9Y2
Antigène
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