TRIP13 anticorps (AA 1-200)
Aperçu rapide pour TRIP13 anticorps (AA 1-200) (ABIN7119956)
Antigène
Voir toutes TRIP13 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-200
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Fonction
- TRIP13 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
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Immunogen sequence: 1-200aa
Immunogen: thyroid hormone receptor interactor 13
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:50-1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))
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Autre désignation
- TRIP13
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Sujet
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Synonyms: Pachytene checkpoint protein 2 homolog|Human papillomavirus type 16 E1 protein-binding protein (16E1-BP, HPV16 E1 protein-binding protein)|Thyroid hormone receptor interactor 13|Thyroid receptor-interacting protein 13 (TR-interacting protein 13, TRIP-13)|TRIP13|PCH2
Background: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks(DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes(By similarity).
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Poids moléculaire
- 49 kDa
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ID gène
- 9319
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UniProt
- Q15645
Antigène
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