TFB2M anticorps

N° du produit ABIN7120070

L’anticorps anti-TFB2M Polyclonal Lapin est utilisé pour la détection de TFB2M dans des échantillons de Humain et Souris. Il a été validé pour ELISA et WB.

Aperçu rapide pour TFB2M anticorps (ABIN7120070)

Antigène: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFB2M est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-TFB2M anticorps

Fonction: TFB2M antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: transcription factor B2, mitochondrial

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur TFB2M

Antigène: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Autre désignation: TFB2M

Sujet:

Synonyms: Dimethyladenosine transferase 2, mitochondrial|Hepatitis C virus NS5A-transactivated protein 5 (HCV NS5A-transactivated protein 5)|Mitochondrial 12S rRNA dimethylase 2|Mitochondrial transcription factor B2 (h-mtTFB, h-mtTFB2, hTFB2M, mtTFB2)|S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2|TFB2M|NS5ATP5

Background: S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.

Poids moléculaire: 45-50 kDa

ID gène: 64216

UniProt: Q9H5Q4