TFE3 anticorps (AA 1-300)

N° du produit ABIN7120074

Cet anticorps anti-TFE3 est un anticorps Lapin Polyclonal détectant TFE3 dans WB, ELISA, IHC et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour TFE3 anticorps (AA 1-300) (ABIN7120074)

Antigène: TFE3 (Transcription Factor E3 (TFE3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFE3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-TFE3 anticorps

Épitope: AA 1-300

Fonction: TFE3 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 1-300aa

Immunogen: transcription factor binding to IGHM enhancer 3

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:200-1:2000, IHC: 1:50-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur TFE3

Antigène: TFE3 (Transcription Factor E3 (TFE3))

Autre désignation: TFE3

Sujet:

Synonyms: Transcription factor E3|Class E basic helix-loop-helix protein 33 (bHLHe33)|TFE3|BHLHE33

Background: Transcription factor that specifically recognizes and binds E-box sequences(5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.

Poids moléculaire: 65 kDa

ID gène: 7030

UniProt: P19532