TNPO2 anticorps

N° du produit ABIN7120247

L’anticorps Lapin Polyclonal anti-TNPO2 a été validé pour WB, ELISA et IF. Il convient pour détecter TNPO2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TNPO2 anticorps (ABIN7120247)

Antigène: TNPO2 (Transportin 2 (TNPO2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNPO2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-TNPO2 anticorps

Fonction: TNPO2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: transportin 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur TNPO2

Antigène: TNPO2 (Transportin 2 (TNPO2))

Autre désignation: TNPO2

Sujet:

Synonyms: Transportin-2|Karyopherin beta-2b|TNPO2

Background: Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals(NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex(NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus(By similarity).

Poids moléculaire: 90-100 kDa

ID gène: 30000

UniProt: O14787