TRIM21 anticorps (AA 76-326)
Aperçu rapide pour TRIM21 anticorps (AA 76-326) (ABIN7120276)
Antigène
Voir toutes TRIM21 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 76-326
-
Fonction
- TRIM21 antibody
-
Purification
- Immunogen affinity purified
-
Pureté
- ≥95 % as determined by SDS-PAGE
-
Immunogène
-
Immunogen sequence: 76-326aa
Immunogen: tripartite motif-containing 21
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- -20°C for 12 months
-
Date de péremption
- 12 months
-
-
- TRIM21 (Tripartite Motif Containing 21 (TRIM21))
-
Autre désignation
- TRIM21
-
Sujet
-
Synonyms: E3 ubiquitin-protein ligase TRIM21|52 kDa Ro protein|52 kDa ribonucleoprotein autoantigen Ro/SS-A|RING finger protein 81|Ro(SS-A)|Sjoegren syndrome type A antigen (SS-A)|Tripartite motif-containing protein 21|TRIM21|RNF81|RO52|SSA1
Background: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.
-
Poids moléculaire
- 54 kDa
-
ID gène
- 6737
-
UniProt
- P19474
Antigène
-