TRIM6 anticorps
Aperçu rapide pour TRIM6 anticorps (ABIN7120296)
Antigène
Voir toutes TRIM6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- TRIM6 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
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Immunogen sequence: 229-422
Immunogen: tripartite motif-containing 6
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- TRIM6 (Tripartite Motif Containing 6 (TRIM6))
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Autre désignation
- TRIM6
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Sujet
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Synonyms: Tripartite motif-containing protein 6|RING finger protein 89|RING-type E3 ubiquitin transferase TRIM6|TRIM6|RNF89
Background: E3 ubiquitin-protein ligase which ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells(By similarity). Involved in the synthesis of unanchored K48-linked polyubiquitin chains which interact with and activate the serine/threonine kinase IKBKE, leading to phosphorylation of STAT1 and stimulation of an antiviral response(PubMed:24882218).
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Poids moléculaire
- 56 kDa
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ID gène
- 117854
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UniProt
- Q9C030
Antigène
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